Abstract
Yellowtail Seriola quinqueradiata were fed on brown fish meal diets supplemented with 40mg/100g of α-tocopherol (α-Toc) and 9% of sardine oil whose POV was 4.7 (group I) or 100 (group II) for 30 days, and changes in a-Toc contents, 2-thiobarbituric acid reactive substances (TBARS) values, and superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) activities in the liver were analyzed. No pathological changes were observed in either group after the experiment. TBARS value and both enzyme activities of group I were lower and the α-Toc content of the group was higher than those of group II. These results suggest that in vivo lipid peroxidation may progress in the liver of yellowtail fed on a diet containing lipid peroxides whose contents are lower than those bringing about pathological changes, and that to suppress in vivo lipid peroxidation α-Toc may be consumed while SOD and GSH-Px might be induced.