A case of metachronous multiple cancers of the pancreas

Abstract

A 70-year-old man admitted to the hospital because of obstructive jaundice. After an ERBD, pancreatoduodenectomy was performed with a diagnosis of carcinoma of the pancreatic head in August 2003. Histological exploration offered a diagnosis of well differentiated tubular adenocarcinoma, T4 (PV) N0, Stage IVa. 9 months after operation, an elevation of CEA and CA19-9 was noted, examinations pointed out dilatation of the MPD of remnant pancreas. After that, an elevation of tumor markers had kept up, CT scan revealed a mass in the remnant pancreas, then total remnant pancreatectomy was performed in July 2005, with a diagnosis of invasive ductal carcinoma derived from IPMT in the remnant pancreas. Histological exploration offered a diagnosis of well to moderately differentiated tubular adenocarcinoma, T4 (PL) N0, Stage IVa. Metachronous invasive ductal carcinoma of the pancreatic head and the remnant pancreas curatively resected is extremely rare.