Abstract
A 53-year-old man had been receiving regular treatment for chronic pancreatitis. He noticed dyspnea and right chest pain. The chest X-ray indicated an accumulation of right pleural effusion along with elevated levels of amylase in the serum and pleural effusion. On the basis of CT and ERP findings, we diagnosed the patient as having an mediastinal pancreatic pseudocyst. The endoscopic pancreatic drainage (EPD) was performed, which decreased the amount of pleural effusion and the level of serum amylase. However, the inflammatory response was elevated and the cyst became enlarged in CT images. A diagnosis of infection due to EPD tube insertion was made and percutaneous cystic drainage was performed. As a result, the inflammatory response was reduced and the cyst disappeared in CT images.