Continuous Glucose Monitoring in the Management of Pancreatic Diabetes Complicated by Pancreatic Insufficiency

Abstract

Digestive enzyme and insulin replacement therapy are needed for patients with pancreatic diabetes complicated by pancreatic exocrine insufficiency. We determine the effect of these treatments based on nutritional assessment and glycemic control. We use HbA1c and glycoalbumin levels for assessment of long-term glycemic control, and SMBG (self-monitoring of blood glucose) to assess the daily blood glucose profile. However, the confirmation of unconscious hypoglycemia and nocturnal hypoglycemia is difficult using these methods.

Continuous glucose monitoring is effective for the confirmation of unconscious hypoglycemia and nocturnal hypoglycemia. Objective assessment of hypoglycemia frequency is enabled by adding "time below target glucose range: TBR" as an assessment item for glycemic control.