Abstract
Mitochondrial encephalomyopathy is a general name for a group of myopathy associated with central nervous symptoms. For MELAS (mitochondria myopathy, encephalopaty, lactic acidosis and stroke-like episodes), important factors for diagnosis are the increase of lactic acid value in blood and cerebro-spinal fluid, stroke-like symptoms, pathological evidence of ragged-red fibers in muscle fiber by Gomori-trichrome staining in muscle biopsy, and abnormal biochmical mitochondrial findings, and it is characterized by diverse clinical features. It is a genetic disease first reported by pavlalkis et al in 1984. We perfomed anesthesia in bilateral foot muscle release operation for a patient with MELAS who had paralytic pes equinovarus (paralytic club foot) showing clinical features different from those found in the past report. The results of our study are reported.
