抄録
Early onset benign childhood occipital seizure (EBOS) is a type of benign childhood partial epilepsy with ictal vomiting and deviation of the eyes. EBOS is typified by multifocal electroencephalogram (EEG) occipital spike discharges. In this study, we investigated the localization of equivalent current dipoles of two EBOS cases using the dipole tracing (DT) method based on the scalp-skull-brain (SSB) head model of individual subjects, and estimated the dipole localization from spike averages. EEG spikes were recorded with scalp EEG surface electrodes (international 10/20 system) . For subject 1, the dipolarity of equivalent current dipoles (ECDs), recorded from the beginning of a spike to the maximum positive peak, was located in the compact area of the right occipital region. The ECDs, recorded from the maximum positive peak to the end of a spike, were located alongside the right optic radiation area. ECDs were located in the right occipital region from the end of the spike to the end of the slow wave. For subject 2, the dipolarity of ECDs was located in the compact occipital area throughout the spikes and waves. The right occipital region was determined to be the visual association cortex or Brodmann area 19. These findings suggest that the occipital region is involved in the mechanism of visual transformation in the visual association cortex.