Abstract
This study examines a method for elucidating the relation between the size distribution of crystals and the local supersaturation distribution obtained from simulation. To apply simulation results to equipment design and process control, one must understand relations prevailing among the distribution of physical quantities, nucleation, and crystal growth. Simulation results obtained for KCl–ethanol anti-solvent crystallization in a Y-shaped channel are used as an example. The trajectory on which crystals move in the channel is specifically examined. The concentrations of the solute and of the anti-solvent on the trajectory are drawn on a ternary phase diagram. The crystal size distribution is indicated as explainable quantitatively from the solute and the anti-solvent concentration and local supersaturation change on the trajectory which are drawn on the ternary phase diagram. Appropriate equipment design and process control conditions might be obtainable from the supersaturation changes on the crystal trajectory obtained using this method.
