Tando
Online ISSN : 1883-6879
Print ISSN : 0914-0077
ISSN-L : 0914-0077
Original Articles
Significance of a gallbladder wall blood flow analysis by Doppler ultrasonography in the diagnosis of gallbladder cancer
Hiroyuki KatagiriMichiko YanagiharaHiroshi EndohShin KumasakaShigeru FujiiKenichiro IshiiYoshihito TakahashiKazunori FurutaMakoto ObuMasahiko Watanabe
Author information
JOURNAL FREE ACCESS

2009 Volume 23 Issue 2 Pages 163-173

Details
Abstract
We reviewed the maximal blood flow velocity (Vmax) in the gallbladder wall (cystic artery) using Doppler ultrasonography in 46 patients (cancer N=14, benign N=32). The Vmax of cancer (45.0±13.2 cm/s) was significantly higher than that observed for chronic cholecystitis, polyps or ADM (adenomyomatosis) (p<0.01). An ROC analysis showed a Vmax cut-off value of 35.2 cm/s, while the sensitivity was 85.7% and the specificity was 88.2%. The histological findings clarified the fibrous hyperplastic change in the intraarterial membrane of the basal area lying under the cancer nest. This alteration was not found in the non-cancer areas, polyps or ADM. These results suggested that stenotic change of the artery may cause an increase in the blood flow velocity. In conclusion, a blood flow analysis makes it possible to directly evaluate cancerous changes in the preoperative examination.
Content from these authors
© 2009 Japan Biliary Association
Previous article Next article
feedback
Top