2019 Volume 33 Issue 5 Pages 878-883
A 63-year-old man was pointed out the pancreatic head tumor at another hospital. He was referred to our hospital for close inspection and treatment. CT showed an early stage enhanced tumor 8mm in diameter at the pancreatic head. ERCP showed a tumor with smooth surface which had protruded into the distal bile duct. A preoperative diagnosis of pancreatic head neuroendocrine tumor was made, and the patient underwent pylorus-preserving pancreaticoduodenectomy. Histological examination revealed growth of atypical cells with funicular and ribbon-like arrangement under the bile duct epithelium. And atypical cells were positive for chromogranin A by immunohistochemical staining. A final diagnosis of neuroendocrine tumor of the distal bile duct was made. The postoperative course was uneventful, and he is alive without recurrence for 8 years after surgery. Since neuroendocrine tumor of the extra bile duct is rare, we report on this case with some bibliographical comments.
