2020 Volume 34 Issue 4 Pages 710-717
The case was a 56-year-old woman. She had anorexia two weeks ago, and then noticed urinary yellow staining and white stool. Abdominal contrast-enhanced CT showed a 15-mm mass in the pancreas head, causing bile duct obstruction. An 83-mm uterus tumor suspected to be malignant and multiple lung and bone metastases were also found. ERCP was performed, a severe stenosis was observed in the distal bile duct. IDUS showed a low echo mass in the pancreatic parenchyma around the stenosis. EUS-FNA was performed for the pancreatic mass, and dense proliferation of spindle cells with atypical nuclei was observed. Immunostaining revealed leiomyosarcoma with SMA (+) desmin (+). The patient was diagnosed with pancreatic metastasis of uterine leiomyosarcoma, and chemotherapy was introduced after biliary stenting. Uterine leiomyosarcoma with obstructive jaundice is rare and is reported with literature review.