2023 Volume 37 Issue 2 Pages 149-154
Background/Aim: Acute colecystitis with unresectable malignant disease is a life-threatening condition. We aimed to investigate the outcome of salvage percutaneous transhepatic gallbladder drainage (PTGBD) in patients with unresectable malignant disease due to failure of management by endoscopic transpapillary gallbladder drainage (ETGBD). Patients and Methods: twenty-one consecutive patients (mean age, 72 years; 62% women) underwent salvage PTGBD between 2013 and 2020. Results: The median overall survival rate was 7.7 months, with a 95% confidence interval (CI) of 3.4-13.1. Independent factors predicting poor outcome were Eastern Cooperative Oncology Group (ECOG) performance status of 4, with a HR of 52.2 (95% CI 1.1-2576.9). Conclusion: Salvage PTGBD has the potential to achieve prolonged survival. Acute cholecystitis in patients with unresectable malignant disease, including those with failure of ETGBD.
