2023 Volume 37 Issue 2 Pages 203-211
A 7X-years old woman had a diagnosis of gallbladder cancer associated with pancreaticobiliary maljunction without bile duct dilatation and performed cholecystectomy (pT2N1M0). Five years later, she was diagnosed with obstructive jaundice and middle bile duct cancer and performed bile duct resection (pT1N0M0). More than 6 years later, she was diagnosed with intrapancreatic bile duct cancer using the EUS-FNA. The case of the metachronous triple biliary tract cancers with pancreaticobiliary maljunction without bile duct dilatation was not found by review of the literature. In patients with pancreaticobiliary maljunction without bile duct dilatation, careful postoperative long-term follow-up should be required for a possible occurrence of metachronous bile duct cancer.