2023 Volume 37 Issue 4 Pages 787-795
We experienced three cases of synchronous multiple gallbladder cancer.
Case 1; an 81-year-old woman. During follow-up for gallstones, a gallbladder tumor was detected, and laparoscopic cholecystectomy was performed. Two lesions in the resected specimen were adenocarcinoma. Gallbladder bed resection and lymph node dissection were performed as additional resections. T2aN0M0 Stage IIA was diagnosed.
Case 2; a 76-year-old man. A gallbladder tumor was detected by abdominal examination, and surgery was performed. There was infiltration in the transverse colon and duodenum. Gallbladder bed resection, subtotal stomach-preserving pancreaticoduodenectomy, and partial transverse colectomy were performed. Two lesions in the resected specimen were adenocarcinoma and T3aN0M0 stage IIIA was diagnosed.
Case 3; a 92-year-old woman. A detailed abdominal examination revealed a gallbladder tumor, and cholecystectomy was performed because of advanced age. The resected specimen revealed four lesions; one was a combination of adenocarcinoma and neuroendocrine carcinoma (NEC) and three were adenocarcinoma, and T2N1M0 stage IIIB was diagnosed.
Multiple gallbladder carcinomas, especially those with NEC, are extremely rare.
