2025 Volume 39 Issue 5 Pages 786-791
A 36-year-old man with a history of hypertension and diabetes was referred to our hospital because of jaundice. Abdominal contrast-enhanced computed tomography identified mild thickening of the distal bile duct wall with delayed enhancement and dilatation of the upstream bile duct. Magnetic resonance imaging demonstrated a low signal intensity on T1WI and a high signal intensity nodule on T2WI in the distal bile duct. Endoscopic retrograde cholangiopancreatography revealed unilateral bile duct compression and stenosis, while intraductal ultrasonography showed a hypoechoic mass in the distal bile duct extending beyond the bile duct wall. Brush cytology confirmed adenocarcinoma. A subtotal stomach-preserving pancreaticoduodenectomy was performed and pathology revealed a primary adenosquamous carcinoma of the bile duct. Herein, we report a case of primary adenosquamous carcinoma of the bile duct in a relatively young patient with characteristic imaging features of an expanding growth pattern.
