2026 Volume 40 Issue 2 Pages 191-197
An 80-year-old man was referred to our hospital with chief complaint of jaundice. Dynamic CT revealed ductal wall thickening with contrast enhancement along the bile duct from just below the confluence of left and right hepatic ducts to the cystic duct confluence, as well as a gallbladder tumor at fundus infiltrating the liver. Bile cytology obtained via ENBD tube was classified as class V. Based on the above findings, we diagnosed synchronous double primary cancers of perihilar cholangiocarcinoma and gall bladder carcinoma. The patient underwent right portal vein embolization, followed four weeks later by a right hemihepatectomy extending to the caudate lobe, along with extrahepatic bile duct resection. Histopathological examination of the resected specimen, revealed that the gallbladder cancer was a mucinous carcinoma, while the perihilar cholangiocarcinoma was moderately differentiated adenocarcinoma, indicating that these two tumors were independent primary tumors. We report this case, because synchronous occurrence of advanced gallbladder carcinoma and cholangiocarcinoma is extremely rare.
