Abstract
Biliary drainage and anti-tumor treatment are important for the treatment of non-resection cases of hilar cholangiocarcinoma. The considerable standard way of biliary drainage was unilateral metallic stenting from recent reports. However, there was no high rebel evidence, and need a more studies. There was no standard antitumor treatment either for locally or metastatic cases. For the locally advanced cancer, photo dynamic therapy reported its efficacy by randomized controlled trial, but radiation therapy had not confirmed. There are no standard systematic chemotherapy, however, recent developed new agent, such as gemcitabine and S-1 showed good results in response rate and median survival. Combination therapy using these 2 drugs also showed good results. In the near future, the standard chemotherapy will be these drugs or these drugs based regimen.
