2 Serratinineと化学的に関連づけられる数種のLycopodium alkaloidの構造

抄録

Recently, the unique structure of serratinine, including its absolute configuration, has been completely established as shown in the formula (I). On the basis of chemical correlation with serratinine, structures of three new alkaloids which were isolated from lycopodium genus plants growing in Japan; 8-deoxyserratinine (II) from Lycopodium serratum Thunb. var. serratum form. intermedium Nakai (Tohogeshiba), serratine (V) and serratinidine (X) from Lycopodium serratum Thunb. var. serratum form. serratum (Hosobatohogeshiba); and two alkaloids which have been reported in the literatures but whose structures have not been settled; fawcettidine (XXII) and fawcettimine (XXV) from Lycopodium fawcettii Lyloid et Underwood growing in Jamaica; were elucidated. The hypothetical biogenetic relationship among these alkaloids was also suggested.