2 キヒトデAsterias' amurensisの卵巣中に含まれるステロイドグリコシドB_1,B_2の化学構造

抄録

Steroidal glycoside sulfates in the ovary of the starfish Asterias amurensis inhibit the maturation of oocytes and the suppression is overcome by the action of a peptide hormone released from the nervous tissue. We have purified from the ovary fraction B which consists of closely related glycosides and determined the structure of the major two designated B_1 and B_2. The structure of glycoside B_1 is 20α-hydroxy-6α-0-{β-D-quinovopyranosyl-(1'→2')-β-D-glucopyranosyl(1'→4')-[β-D-quinovopyranosyl(1'-2')]-β-D-xylopyranosyl-(1'-3')-β-D-quinovopyranosyl}-3β-sulfo-oxy-5α-cholesta-9(11),24-diene. The structure of glycoside B_2 is 20ξ-hydroxy-6α-0-{β-D-quinovpyranosyl-(1'→2')-β-D-galactopyranosyl(1'→4')-[β-D-quinovopyranosyl(1'→2')]-β-D-xylopyranosyl(1'→3')-β-D-quinovopyranosyl}-3β-sulfo-oxy-5α-cholest-9(11)-en-23-one.