From the aerial part of Hydrangea macrophylla f. macrophylla, new secoiridoid glucosides, hydrangenosides B, C and D have been isolated along with hydrangenoside A which had been encountered in the same plant. On the other hand, hydrangenosides C, D, E, F, G and H of the same series have been isolated from Hydrangea scandens. On the basis of their spectral data and chemical evidence, novel type structures of these new glucosides have been established, which are considered to be formed by an aldol type condensation of secologanin with shikimate-malonate-derived moieties.
