2011 Volume 14 Issue 1 Pages 80-86
A64-year-old woman was admitted to our hospital suffering from a rapidly progressive foot edema and a bloating sensation for six weeks. Based on these symptoms we suspected carcinomatous peritonitis and malnutrition, and performed abdominopelvic enhanced CT and aspiration of ascites. CT showed big folds of gastric mucosa, but histology of ascites was negative. We also performed esophagogastroduodenoscopy, but histology of gastric mucosa showed only foveolar hyperplasia with interstitial lymphocytic infiltration. We detected Helicobacter pylori infection with a positive urea breath test. Eradication therapy for Helicobacter pylori improved all of her symptoms about ten days after the eradication, and she was discharged. She was finally diagnosed as having Ménétrier's disease with Helicobacter pylori infection. We reported Ménétrier's disease as a rare case in the differential diagnosis of rapidly progressive anasarca.