Tetsu-to-Hagane
Online ISSN : 1883-2954
Print ISSN : 0021-1575
ISSN-L : 0021-1575
Biological Activity of the Polysaccharide Produced by the Marine Phytoplankton Porphyridium sp. and Additive Effect of Slag on the Polysaccharide Production
Hiroko SAKAMOTOHideyuki TORADAKentaro GOTOYasue NAKAMURAToshiki NAKANOToshiyasu YAMAGUCHIMinoru SATOTadao SAITOAkira TANIGUCHITakehiko YOKOYAMANobuhiro KAN-NOEizou NAGAHISA
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2003 Volume 89 Issue 4 Pages 475-481

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Abstract

Marine phytoplankton Porphyridium sp. produced and secreted a mucilaginous polysaccharide in the incubation medium. The polysaccharide production was enhanced by the addition of slag at proper concentration. This polysaccharide showed a moderate mitogen activity, similar to dextran sulfate but lower than concanavalin A and lipopolysaccharide. Polysaccharide was found to have antitumor activity against Sarcoma 180 inoculated in the peritoneal cavity of ddY mice.

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© The Iron and Steel Institute of Japan
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