Trends in Glycoscience and Glycotechnology
Online ISSN : 1883-2113
Print ISSN : 0915-7352
ISSN-L : 0915-7352
MINIREVIEW
Chemistry Based Approach for Degradation of Target-Oligosaccharides Using Photo-Activatable Organic Small Molecules
Daisuke TakahashiKazunobu Toshima
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2012 Volume 24 Issue 140 Pages 258-276

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Abstract
Molecular design, chemical synthesis, and biological evaluation of several organic small molecules, which can target-selectively photodegrade oligosaccharides by irradiation with a specific wavelength of light under mild conditions without any additives, are introduced. These novel class of photochemical agents promise bright prospects for finding not only molecular-targeted bioprobes for understanding of the structure-activity relationships of oligosaccharides but also novel therapeutic drugs targeting biologically active oligosaccharides.
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© 2012 FCCA(Forum: Carbohydrates Coming of Age)
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