An Orthogonal Point of View

抄録

My research was initiated when studying oligosaccharide synthesis. Besides my poor attitude toward this area of study, too many synthetic steps are required for the functional group protection and key coupling reactions in oligosaccharide synthesis. When starting an actual experiment, another difficulty that arises is the complex techniques used in the synthesis of oligosaccharides, which is experienced by most students. Despite these difficulties, oligosaccharide synthesis has already become a widely studied research topic; yet, its successful automation is still to be accomplished. An ideal oligosaccharide synthesis utilizes a simple yet flexible synthetic strategy, which is urgently required. Thus, to overcome the limitations associated with its synthesis and to satisfy the need of an ideal process, I came up with an idea of orthogonal coupling strategy for the synthesis of oligosaccharides.