Abstract
Carbohydrates, sometimes in the form of oligosaccharides, are deeply involved in a wide range of biological phenomena including metabolism, intercellular recognition, and infection, etc. Adding the fact that the expression of some glycosyltransferase is directly related to metastasis, it is important to pursue a research into the recognition mechanism between carbohydrates and proteins, which may lead to the discovery of new therapeutic treatment. However, our current knowledge regarding these bindings limits designing and creating potent inhibitors of such interactions. Combinatorial chemistry, therefore, is considered very useful and important in discovering what we are looking for. Another aspect of carbohydrates is that they consist of continuous chiral centers, which can be utilized as a scaffold. This review attempts to summarize the current growth area of carbohydrate based library synthesis. Research, which describes ideas aiming at a carbohydrate library and is very important in the future, had to be omitted.
