Trends in Glycoscience and Glycotechnology
Online ISSN : 1883-2113
Print ISSN : 0915-7352
ISSN-L : 0915-7352
Easy Access to Cell Surface Oligosaccharide Mimics
Carbohydrate Module Approach
Yoshihiro NishidaHirofumi DohiKazukiyo Kobayashi
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JOURNAL FREE ACCESS

2005 Volume 17 Issue 94 Pages 59-69

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Abstract
Obviously, human oligosaccharides and their mimics possess high potential in applications to medicines and biomaterials. On the other hand, it holds true that the high potential stems from the rather complicated and labile chemical structures. Therefore, it is of major significance to elucidate the key structures encoded in the oligosaccharides for making effective “minimization” and “functionalization.” Moreover, the glycosidic linkages labile to acids and glycosidases may give problems to practical applications. In this review, we wish to describe our mimetic design of the cell surface oligosaccharides based on “key carbohydrate modules” and “carbohydrate module method.”
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© FCCA, Forum; Carbohydrates Coming of Age
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