739 cases of Habu snake bite occurred in Amami and Ryukyu Islands in 1964. 109 severe cases were found in 635 cases which were surveyed by us. 72 patients in the severe cases with hypotension, vomitting or other generalized toxic symptoms recovered by the antivenin and other treatment. Severe necrosis of muscles occurred in 15 cases in which 9 cases were led to ankylosis or deformity. 23 cases showed both severe necrosis and generalized symptoms including shock in which 5 died in 24 hours after the envenomations and 11 cases were led to motor disturbances. Severe necrosis frequently occurred in the cases of envenomation of hands or lower legs.
Serum sickness was found in 86 cases in which 79 were delayed type and the remaining cases were immediate type.
