1996 年 24 巻 1 号 p. 1-4
Subcellular antigen localization in Toxoplasma gondii was studied by immunoelectron microscopy using sera obtained from congenital toxoplasmosis neonates or the mother. IgG and IgM antibodies bound specifically to the dense granules and rhoptries, but little bound to the cytoplasm of the organism or its tegmentum. The results indicate the importance of dense granules and rhoptries as a storage site for the antigens, which would be released and stimulate antibody production in human toxoplasmosis.