Sensitized Generation of Singlet Oxygen by Allylamine-Terminated Hydrophilic Porous Si

抄録

We studied the sensitized generation of singlet oxygen by surface-modified hydrophilic porous Si. Porous Si consisting of a network of Si nanocrystals acts as an efficient photosensitizer for the generation of exited state molecular oxygen called singlet oxygen. Singlet oxygen is widely used in chemistry and biology. One of the possible applications of it is photodynamic therapy of cancer (PDT). However, as-prepared porous Si is hydrophobic and thus cannot be used as singlet oxygen photosensitizer in aqueous solution. Therefore, in this work, we modified the surface of porous Si by organic molecules (allylamine). We found that allylamine-terminated hydrophilic porous Si holds the photosensitization ability, although the efficiency of singlet oxygen generation is reduced by the modification.