抄録
Glyco-dendrimers carrying sulfate saccharides were efficiently synthesized via a cycloaddition of click chemistry. The interactions with a lectin of wheat germ agglutinin were evaluated by fluorescence spectroscopy. The interactions with amyloid p peptide were evaluated by CD spectra, thioflavin T assays and AFM observation. The interaction with the lectin and amyloid P peptide were affected by the size of the dendrimer and the kind of saccharide.
