2009 年 34 巻 1 号 p. 89-91
Improvement of bone integration ability of metallic biomaterials is needed for long-term stable fixation to bone tissues. Essential prerequisite for materials to show bone-integrating bioactivity is formation of apatite layer on their surfaces in body environments. Several functional groups have potential to trigger the apatite nucleation. In the present study, we attempted fabrication of bioactive titania layer which provides Ti-OH groups effective for the apatite formation on bioinert metals such as stainless steel and Co-Cr-Mo alloys by electrodeposition. Their bioactivity was evaluated in vitro in simulated body fluid (SBF). Bioactive titania layer was fabricated on both metals after heat treatment at appropriate temperature. Co-Cr-Mo alloys showed a tendency to form larger amount of the apatite than the stainless steel at the same temperature of heat treatment. This phenomenon was attributed to intergranular corrosion on the stainless steel and apatite depostion on the heat-treated stainless steels without the titania coating.
