抄録
Many infectious animal diseases that could not be controlled well by vaccination, including foot-and-mouth disease (FMD) and highly pathogenic avian influenza (HPAI), have occurred in many countries, especially across Asia. Materials that can enhance biosecurity in farms are important. In Japan, slaked lime has been used as disinfectant in farms, but it has a toxic effect on animals, as well as humans, and is easy to lose antiviral activity by oxidation. The desirable materials should be safe, cost effective, and long life. Aomori prefecture in Japan is very famous for culture of scallops. The scallop-shells after calcination process become powder and the main content of the powder is calcium oxide (CaO) that has bactericidal effects. Here we demonstrated antiviral activity of scallop-shell powder and its long life of antiviral activity against avian influenza virus (AIV) and goose parvovirus (GPV). Scallop-shell powder could reduce viral titers of AIV and GPV more than 10,000 times to undetectable level within 3 minutes. When the powder was spread on containers or on a chicken farm, its antiviral activity lasted more than 8 months. Scallop-shell powder seems to be a good candidate of materials for enhancement of biosecurity in farms.
