Abstract
A 36-year-old man seen for hyperglycemia and ketosis was started on multiple insulin injections. Two weeks later, he was hospitalized for swelling, redness, and pain in the left thigh. Magnetic resonance imaging (MRI) of the thighs indicated diabetic muscle infarction. Symptoms resolved spontaneously within three weeks. Diabetic muscle infarction, a rare diabetes complication, is usually seen in subjects with long-term poorly controlled type 1 diabetes associated with advanced diabetic complications. Our subject, in contrast, had short-term type 2 diabetes free of complications such as nephropathy, retinopathy, or neuropathy. Even so, alternating glycemic states after insulin injections are started may be responsible for muscle infarction.