Abstract
In a series of twenty-five children (0-14 years) born of diabetic mothers, the congenital abnormalities, the bone development, the neuropsychological development and the glucose tolerance were studied. The results are summarized as follows.
(1) Eighteen of the 25 children showed normal weight andheight of their age, 4 overweight with normal height, 2 normal weight with low height, and one underweight and low height.
(2) No congenital major abnormalities were observed, however minor ones were observed in eleven children (44%)
(3) Nineteen of twenty-two children showed normal development of the bones, and three delayed.
(4) None showed mental retardation.
(5) Fifteen of twenty-one children showed normal findings of EEGs, 4 borderline ones, and 2 abnormal ones.
(6) One-hundred gram-OGTT was examined in thirteen children. Eleven of them showed normal blood glucose patterns, and two borderline ones.
Four of them showed low insulin responses, one delayed response, 2 hyperresponses, and 6 normal responses.
