Abstract
Human plasma growth hormone (HGH) was determined during moderate muscular exercise in two comparable groups of male nonobese diabetics. One group contained 6 diabetics without retinopathy and 3 diabetics with background retinopathy. Another group consisted of 10 diabetics with proliferative retinopathy. Despite the metabolic similarities between the two groups, the HGH response to muscular exercise was significantly higher in the second group with proliferative retinopathy than in the first group without proliferative retinopathy. These results suggest a hyperresponseof HGH release in diabetics with proliferative retinopathy following considerable muscular exercise.