Abstract
We eperienced a pair of identical twins who developed IDDM (insulin-dependent diabetes mellitus) on the same day. Among their family members, the maternal uncle had non-insulin-dependent diabetes. In previous reports we were not able to find a pair of twins whose clinical onset was on the same day. Both twins had HLA-A 2, A 24, B 38, Bw 54, Cw 3, DR 4, DRw 9, a typical type of Japanese IDDM. Their HLA type was thought to be one of the risk factors for IDDM.
They developed diabetes on the second day of school excursion. It was thought that the main factor leading to diabetes on the same day was their drinking a lot of juice and eating many sweets during the school excursion.