Abstract
A spectral analysis of changes in R-R interval was parformed at rest and during deep breating by the maximum entropy method (MEM) and compared between patients who showed sympathetic skin respones (SSR) omission a low amplitude or no response and normal responses, then SSR was further compared with findings on myocardial scintigraphy (SPECT) using changes in the low-frequency range.
The standard deviation and hinge spread of variation range of R-R interval and values of segmental integration were significantly increased in the high-frequency range after deep breathing, reflecting parasympathetic nerve function. But in the low-frequency range, reflecting sympathetic nerve function, the value of segmental integration had already decreased at rest and no increase after deep breathing was observed on SSR test in patients with impaired autonomic nervous function who showed by myocardial scintigraphy (SPECT) or prolongation of latency and a clear decrease in the amplitude of SSR or no responses.
In power spectral analysis of the variation range of R-R interval recorded with SRR-5 on ECG using MemCalc 1000, the change in the value of segmental integration in the low-frequecy range during deep breathing was considered to be a useful clinical index for the evaluation of sympatheti nerve function in patients with diabetes mellitus.