Journal of Toxicologic Pathology
Online ISSN : 1881-915X
Print ISSN : 0914-9198
ISSN-L : 0914-9198
FINE STRUCTURAL CHANGES OF THE ORGANELLES DURING ENZYME INDUCTION IN HEPATOCYTES
Katsuhiro OgawaTatsuro TakahashiShunji Muraoka
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1989 Volume 2 Issue 1 Pages 1-9

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Abstract
Hepatocytes have a great capability to adapt to functional demand by changing enzyme activity. In this report, ultrastructural characteristics were described in developing, regenerating and drug-exposed hepatocytes in which various enzymes are rapidly synthesized. A brief review was made on the mechanism as to how the enzymes are transported from the site of synthesis and assembled to the organelles.
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© The Japanese Society of Toxicologic Pathology
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