β-ナフトフラボンによるラット肝発癌促進過程において発現変動が認められる薬物代謝酵素・細胞増殖関連分子の発現局在について

出羽 康明; 西村 次平; 金 美蘭; 川合 正臣; 三枝 由紀恵; 渋谷 淳; 三森 国敏

doi:10.14869/toxp.35.0.76.0

The 35th Annual Meeting of the Japanese Society of Toxicology

Session ID : O-11

DOI https://doi.org/10.14869/toxp.35.0.76.0

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2. Carcinogenesis

Molecular expression analysis of drug metabolizing enzymes and cell cycle-related genes fluctuated during beta-naphthoflavone-induced tumor promotion in rats liver

*YASUAKI DEWA, JIHEI NISHIMURA, MEILAN JIN, MASAOMI KAWAI, YUKIE SAEGUSA, MAKOTO SHIBUTANI, KUNITOSHI MITSUMORI

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*YASUAKI DEWA
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
JIHEI NISHIMURA
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
MEILAN JIN
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
Department of Applied Biological Science, United Graduate School of Agricultural Sciences, Tokyo University of Agriculture and Technology
MASAOMI KAWAI
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
YUKIE SAEGUSA
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
MAKOTO SHIBUTANI
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
KUNITOSHI MITSUMORI
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology

Keywords: beta-naphthoflavone, Non-genotoxic hepatocarcinogen, Aryl hydrocarbon receptor

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