Host: The Japanese Society of Toxicology
Name : The 47th Annual Meeting of the Japanese Society of Toxicology
Date : 2020 -
Recently cryo-electron Microscopy (cryoEM) are drawing attention as new technology, as it is likely to provide structure information on large and flexible proteins such as channels, transporters, or complexes. Through revealing structure information of those proteins, it is expected to improve efficiency to reduce off-target liability by SBDD approach.
As toxicity related proteins or pharmacokinetics related proteins are common among pharmas, we are collaborating to obtain structure information on non-competitive proteins. In this symposium, I would like to introduce our attempts and discuss future opportunities for cryoEM technology.
