Annual Meeting of the Japanese Society of Toxicology
The 47th Annual Meeting of the Japanese Society of Toxicology
Session ID : S28-5
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Symposium 28
Overview of AMED-MPS project; User-driven Microphysiological System (MPS) development
*Hitoshi NARAOKA
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CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract

The National MPS project in Japan (AMED-MPS) consists of 4 research teams, central research center, and Head Quarter for establishing a close communication system among academic researchers, pharmaceutical companies as users and decision makers.

The main research program is organ model development research program focusing on cell supply and MPS model development of 4 organs: liver, gut, kidney, and BBB. In addition to the main research program, industrial programs are involved including the device manufacturing research program developing manufacturing technology for industrially produces; standardization research program developing standardization of MPS models for quality control and regulatory development in AMED-MPS. Noteworthy, senior managers and researchers in pharmacokinetics, safety fields from domestic pharmaceutical companies participate in the project as a member of decision-making body and research partners.

To bridge between the researchers and users, Central-research-center, closely collaborating with manufacturing and standardization program members, conducts researches and development to transfer newly-developed MPS technologies from model development team into practical use in users.

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© 2020 The Japanese Society of Toxicology
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