Annual Meeting of the Japanese Society of Toxicology
The 51st Annual Meeting of the Japanese Society of Toxicology
Session ID : S17-3
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Symposium 17: Biometric analysis technology linked to morphology
Proteomic analysis technology for pathological elucidation using FFPE tissue samples
*Tomoaki MURAKAMI
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CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract

In experimental pathology research, fresh material is typically used for analysis. On the other hand, fresh materials are difficult to obtain for pathology studies of spontaneous cases, and formalin-fixed paraffin-embedded (FFPE) samples are often the only resource available for analysis. This has previously limited the contribution of case-based studies to elucidate disease states. However, recent technological advancements have expanded the possibilities for analyzing FFPE samples, including proteomic analysis. This has opened up new avenues for case-based studies to contribute to understanding disease states. In this talk, I will explore how to extract valuable information from limited resources, focusing on animal amyloidosis, a key theme of the speaker's research. Specifically, I will discuss proteomic analysis using FFPE samples from spontaneous cases and how it can elucidate pathomechanisms.

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