Host: The Japanese Society of Toxicology
Name : The 51st Annual Meeting of the Japanese Society of Toxicology
Date : July 03, 2024 - July 05, 2024
In experimental pathology research, fresh material is typically used for analysis. On the other hand, fresh materials are difficult to obtain for pathology studies of spontaneous cases, and formalin-fixed paraffin-embedded (FFPE) samples are often the only resource available for analysis. This has previously limited the contribution of case-based studies to elucidate disease states. However, recent technological advancements have expanded the possibilities for analyzing FFPE samples, including proteomic analysis. This has opened up new avenues for case-based studies to contribute to understanding disease states. In this talk, I will explore how to extract valuable information from limited resources, focusing on animal amyloidosis, a key theme of the speaker's research. Specifically, I will discuss proteomic analysis using FFPE samples from spontaneous cases and how it can elucidate pathomechanisms.