Effects of prostaglandin E₁ infusion on blood flow in a patient with Buerger's disease: a case report

抄録

A 45-year-old male patient with Buerger's disease presented with intermittent claudication, sharp rest pain in his right foot, and several episodes of lower extremity superficial thrombophlebitis. He had no cardiovascular risk factors and his glucose levels were within normal ranges. However, he had a smoking history of more than 26 years; he had stopped smoking 3 years prior. Early treatment with antithrombotic and vasodilating agents as well as intravenous infusion of prostaglandin E₁ did not improve his condition. Intra-arterial infusion of prostaglandin E₁ once a day for 2 weeks slightly increased blood flow in the areas with previous low blood flow and improved his condition from Fontaine stage III to II.