論文
Chirality of the Very First Molecule in Absolute Enantioselective Synthesis
2007 年 35 巻 3 号 p. 82-84
詳細
2007 年 35 巻 3 号 p. 82-84
In the present paper the role of the very first chiral molecule formed in achiral-to-chiral reactions, is discussed. This molecule represents obligatorily 100 % ee, with important consequences for absolute enantioselective synthesis. Calculations show that Soai-type autocatalytic reactions could amplify even one molecule initial enantiomeric excess to high ee under reasonable conditions, which enables also an experimental control.
