Abstract
Water soluble disulfonates of thiamine were prepared by exchange of anionic group of thiamine chloride hydrochloride with anion exchange resin, or by adding the aqueous solution of thiamine sulfate to the aqueous solution of barium sulfonate followed by the removal of barium sulfate resulted. Disulfonates of thiamine and oxythiamine, both less soluble in water, were prepared by adding the aqueous soltion of chloride hydrochloride of thiamine or oxythiamne to the aqueous solution of sulfonic acid or alkali sulfonate. Monosulfonates of thiamine, less soluble in water, were prepared by adding the aqueous solution of thiamine mononitrate to the aqueous solution of alkali sulfonate, or by treating the solution of the corresponding thiamine disulfonate with barium carbonate.
