Abstract
After orally administering 500 μg of solubilized vitamin A to rats, changes in the levels of the vitamin in liver as well as in serum were followed and compared with the case with the vitamin dissolved in oil. The maximum level in the liver was reached about 9 hours after administering the solubilized vitamin, whereas about 15 hours after administering the vitamin in oil, the highest value of the fromer being about 1.6 times that of the latter. The rise in each hour was always higher in the former than in the latter. The level of the vitamin in serum was highest about 2 hours after administration in the case of the solubilized vitamin, whereas about 4 hours in the case of the vitamin in oil, the highest value being about 1.8 times that of the latter. In short, the solubilized vitamin A is markedly more easily absorbed and utilized than the vitamin in oil.
