PHARMACOLOGICAL STUDIES ON OXYMETHYLPYRIMIDINE : (IV) ON THE PRINCIPAL CAUSE OF ACUTE TOXIC DEATH BY OMP

Abstract

The principal cause of the acute toxic death of animals with OMP was the cardiovascular disturbance due to the repeated convulsions, except in the case of small animal such as mice. The death with INAH convulsion was led by the respiratory paralysis. If an adequate dose of sodium diethylbarbiturate was injected to the rabbit in convulsion before the rabbit fell into shock, the convulsion was mitigated and the animal survived.