Abstract
In order to study the function of the liver in vitamin A metabolism, the following experiments were made. A definite amount of aqueous emulsion of vitamin A-palmitate was injected into the femoral vein of a healthy dog and the determination of serum vitamin A alcohol and its ester contents of arterial and hepatic venous blood was carried out before injection and 5,30,60 and 120 minutes after injection. The blood was taken out with a liver catheter. A considerable amount of vitamin A ester administered intravenously was taken up in the liver. A part of vitamin A ester taken up into the liver was hydrolyzed to vitamin A alcohol and then returned to blood as free form.
