Abstract
It is worthy to note that #1-19,a mutant strain of E.coli, responds to both of pantothenate moieties, β-alanine and pantoyl lactone. Metabolic accumulation of pantothenate precursors by pantothenate auxotrophs was studied, and the accumulation of β-alanine in pantoic-less culture and the pantoyl moiety in a β-alanine-less culture was demonstrated. Both of the two moieties were also demonstrated in a culture of preformed pantothenate requiring mutants. Neither of the moieties was, however, demonstrated in the cultures of #1-19 and of the parent strains.
