EFFECT OF ANTIBIOTICS ON THE NUTRIENT METABOLISM OF LACTIC ACID BACTERIA : (VIII) DECOMPOSITION OF CHLORAMPHENICOL INTO PABA BY LACTOBACILLUS ARABINOSUS 17-5
The pathway of decomposition of chloramphenicol into PABA by Lactobacillus arabinosus 17-5 was postulated from the results obtained by paper chromatography, and was proved from the results obtained by its growth test. This pathway differs from that postulated by Smith and Worrel, and is summarized as follows : Chloramphenicol→1-p-nitrophenyl-2-amino-1,3-propanediol→α-amino-β-hydroxy-p-nitropropiophenone→(p-nitrobenzoic acid)→p-aminobenzoic acid
