Abstract
Studies were made on the effects of riboflavin derivatives upon the disorder of tryptophan metabolism caused by the liver injury. When tryptophan had been administered, the liver injured rats excreted a higher amount of xanthurenic acid, and a smaller amount of kynurenine and anthranilic acid than the normal rats. When riboflavin derivatives had been given with tryptophan, a more remarkable decrease of anthranilic acid and kynurenine and a slight increase of N-methylnicotinamide in the urine were observed, and FMN caused a remarkable decrease of xanthurenic acid excretion.
